Parathyroid
Analysis of Preoperative Predictors of Single and Multiligand Primary Hyperparathyroidism
March 24, 2023
Frye CC, Sanka SA, Sullivan J, Brunt LM, Gillanders WE, Pandian TK, Brown TC. Analysis of Preoperative Predictors of Single and Multigland Primary Hyperparathyroidism. J Surg Res. 2023 Mar 24;288:148-156. doi: 10.1016/j.jss.2023.02.011. Epub ahead of print. PMID: 36966595.
Magnitude of parathyroid hormone elevation in primary hyperparathyroidism: Does time of day matter?
October 28, 2022
Frye CC, Sullivan J, Sanka SA, Liu J, Brunt LM, Gillanders W, Brown TC, Pandian TK. Magnitude of parathyroid hormone elevation in primary hyperparathyroidism: Does time of day matter? Surgery. 2023 Mar;173(3):659-664. doi: 10.1016/j.surg.2022.07.051. Epub 2022 Oct 29. PMID: 37534706.
Parathyroid-Targeted Overexpression of Regulator of G-Protein Signaling 5 (RGS5) Causes Hyperparathyroidism in Transgenic Mice
February 28, 2019
Balenga N, Koh J, Azimzadeh P, Hogue J, Gabr M, Stains JP, Olson JA Jr. Parathyroid-Targeted Overexpression of Regulator of G-Protein Signaling 5 (RGS5) Causes Hyperparathyroidism in Transgenic Mice. J Bone Miner Res. 2019 May;34(5):955-963. doi: 10.1002/jbmr.3674. Epub 2019 Feb 28. PMID: 30690792; PMCID: PMC8210536.
Polyclonal origin of parathyroid tumors is common and is associated with multiple gland disease in primary hyperparathyroidism
January 1, 2019
Shi Y, Azimzadeh P, Jamingal S, Wentworth S, Ferlitch J, Koh J, Balenga N, Olson JA Jr. Polyclonal origin of parathyroid tumors is common and is associated with multiple gland disease in primary hyperparathyroidism. Surgery. 2018 Jan;163(1):9-14. doi: 10.1016/j.surg.2017.04.038. PMID: 29254595; PMCID: PMC5738672.
Reporter gene assays for investigating GPCR signaling
September 1, 2017
Azimzadeh P, Olson JA Jr, Balenga N. Reporter gene assays for investigating GPCR signaling. Methods Cell Biol. 2017;142:89-99. doi: 10.1016/bs.mcb.2017.07.006. Epub 2017 Sep 1. PMID: 28964343.
Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling
November 25, 2016
Balenga N, Azimzadeh P, Hogue JA, Staats PN, Shi Y, Koh J, Dressman H, Olson JA Jr. Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling. J Bone Miner Res. 2017 Mar;32(3):654-666. doi: 10.1002/jbmr.3023. Epub 2016 Nov 25. PMID: 27760455; PMCID: PMC7211037.
Single-cell functional analysis of parathyroid adenomas reveals distinct classes of calcium sensing behaviour in primary hyperparathyroidism
December 5, 2015
Koh J, Hogue JA, Wang Y, DiSalvo M, Allbritton NL, Shi Y, Olson JA Jr, Sosa JA. Single-cell functional analysis of parathyroid adenomas reveals distinct classes of calcium sensing behaviour in primary hyperparathyroidism. J Cell Mol Med. 2016 Feb;20(2):351-9. doi: 10.1111/jcmm.12732. Epub 2015 Dec 5. PMID: 26638194; PMCID: PMC4727552.
Functional and genetic studies of isolated cells from parathyroid tumors reveal the complex pathogenesis of parathyroid neoplasia
February 7, 2014
Shi Y, Hogue J, Dixit D, Koh J, Olson JA Jr. Functional and genetic studies of isolated cells from parathyroid tumors reveal the complex pathogenesis of parathyroid neoplasia. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3092-7. doi: 10.1073/pnas.1319742111. Epub 2014 Feb 7. PMID: 24510902; PMCID: PMC3939880.
Regulator of G protein signaling 5 is highly expressed in parathyroid tumors and inhibits signaling by the calcium-sensing receptor
March 10, 2011
Koh J, Dar M, Untch BR, Dixit D, Shi Y, Yang Z, Adam MA, Dressman H, Wang X, Gesty-Palmer D, Marks JR, Spurney R, Druey KM, Olson JA Jr. Regulator of G protein signaling 5 is highly expressed in parathyroid tumors and inhibits signaling by the calcium-sensing receptor. Mol Endocrinol. 2011 May;25(5):867-76. doi: 10.1210/me.2010-0277. Epub 2011 Mar 10. PMID: 21393447; PMCID: PMC3082322.
Parathyroid carcinoma: current understanding and new insights into gene expression and intraoperative parathyroid hormone kinetics
January 5, 2010
Adam MA, Untch BR, Olson JA Jr. Parathyroid carcinoma: current understanding and new insights into gene expression and intraoperative parathyroid hormone kinetics. Oncologist. 2010;15(1):61-72. doi: 10.1634/theoncologist.2009-0185. Epub 2010 Jan 5. PMID: 20051478; PMCID: PMC3227890.
Thyroid
Immune cell infiltrate-associated dysregulation of DNA repair machinery may predispose to papillary thyroid carcinogenesis
August 19, 2019
Nicolson NG, Brown TC, Korah R, Carling T. Immune cell infiltrate-associated dysregulation of DNA repair machinery may predispose to papillary thyroid carcinogenesis. Surgery. 2020 Jan;167(1):66-72. doi: 10.1016/j.surg.2019.02.024. Epub 2019 Aug 19. PMID: 31439400.
Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing
January 9, 2015
Kunstman JW, Juhlin CC, Goh G, Brown TC, Stenman A, Healy JM, Rubinstein JC, Choi M, Kiss N, Nelson-Williams C, Mane S, Rimm DL, Prasad ML, Höög A, Zedenius J, Larsson C, Korah R, Lifton RP, Carling T. Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing. Hum Mol Genet. 2015 Apr 15;24(8):2318-29. doi: 10.1093/hmg/ddu749. Epub 2015 Jan 9. PMID: 25576899; PMCID: PMC4380073.
Frequent silencing of RASSF1A via promoter methylation in follicular thyroid hyperplasia: a potential early epigenetic susceptibility event in thyroid carcinogenesis
November 1, 2014
Brown TC, Juhlin CC, Healy JM, Prasad ML, Korah R, Carling T. Frequent silencing of RASSF1A via promoter methylation in follicular thyroid hyperplasia: a potential early epigenetic susceptibility event in thyroid carcinogenesis. JAMA Surg. 2014 Nov;149(11):1146-52. doi: 10.1001/jamasurg.2014.1694. PMID: 25229773.